A randomized control trial was conducted with 53 healthy participants for upto 12 weeks. The results of this study showed that both these diets have different impacts on the metabolism, cholesterol levels and gut microbiome of the body.
Free-sugar restriction diet minimally affects metabolism or gut microbiome but decreases Low Density Lipoproteins (LDL-C).
On the other hand, a ketogenic diet decreases glucose tolerance, increases apolipoprotein-B and alters gut microbial beta diversity.
The data from the research result showed that restricting free-sugars or overall carbohydrates reduces energy intake without altering physical activity, but with divergent effects on glucose tolerance, lipoprotein profiles and gut microbiome.
Reference:
Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype and gut microbiome: RCT. / Hengist, Aaron; Davies, Russell; Walhin, Jean-Philippe et al. In: Cell Reports Medicine, 20.08.2024.
